Rich Pipeline With Significant Opportunities
Product Target Indications Preclinical Ph I Ph II NDA Trial Regions Rights regions
HQP1351 BCR-ABL/KIT Resistant CML
   
 
GIST
 
Ph + ALL
 
APG-2575 Bcl-2 Selective CLL/SLL
   
WM
AML
MM
T-PLL
Solid tumors
ER+/HER2- Breast Cancer
MDS
APG-115 MDM2-p53 Solid tumors(IO combo)
   
AML,MDS
APG-1387 IAP/XIAP Solid tumors + IO
   
PDAC + Chemo
 
HBV
 
APG-1252 Bcl-2/Bcl-xL NSCLC + TKI
   
MF
 
NET
 
APG-2449 FAK/ALK/ROS1 NSCLC / Solid tumors
   
APG-5918 EED Selective Oncology/Hemoglobinopathy
   
APG-265 PROTACs MDM2 Oncology

   
UBX1967/1325 Bcl family DME

   
POC
POC in progress