Press Releases

Rockville, Maryland and Hong Kong—February 14, 2019— Ascentage Pharma, a global clinical-stage biopharmaceutical company dedicated to developing apoptosis-targeted therapies for cancers and other diseases, today announced the appointment of Jeff Kmetz as Chief Business Officer. Mr. Kmetz has over 25 years of global pharmaceutical and biotechnology industry experience, most recently serving as Chief Business Officer Read More ›

中国苏州、中国香港和美国马里兰州罗克维尔2019年1月10日—亚盛医药宣布，国家卫生计生委医药卫生科技发展研究中心日前正式下发《关于“重大新药创制”科技重大专项2018年度立项课题的通知》，公司申报的“国内首个原创抗耐药Bcr-Abl抑制剂HQP1351的临床研究及获批生产”、“国际原创新靶点BCL-2抑制剂APG-1252临床开发”和“国际原创新靶点MDM2-p53抑制剂APG-115临床研究及生产注册”3个项目均获立项支持。同时公司申报的“cIAPs拮抗剂APG-1387的临床应用开发”获“十三五”“艾滋病和病毒性肝炎等重大传染病防治”科技重大专项立项支持。 国家“重大新药创制”科技重大专项自2008年开始实施，其总体目标是针对恶性肿瘤等严重危害我国人民健康的十类重大疾病，研制一批重大药物，完善国家药物创新体系，提升自主创新能力，加快医药产业发展，加速我国由仿制向创新、由医药大国向强国的转变。“十三五”期间为实现专项总体目标的跨越发展阶段，自主创新药物与急需品种研发取得重大突破是这一期间的重要目标之一。 亚盛医药董事长杨大俊博士表示：“我们非常高兴公司的多个核心品种获得‘十三五’国家‘重大新药创制’科技重大专项支持。这四个品种均瞄准目前尚未解决的临床需求，如小细胞肺癌、耐药性CML（慢性髓性白血病）、肉瘤、乙肝等，具有较高的临床和社会价值。在专项的支持下，我们将继续推进这些品种及公司其他创新药物的研发进程，力争早日将产品推向上市，为中国乃至全球患者提供更多的治疗选择。” 关于亚盛医药 亚盛医药是一家立足中国、面向全球的处于临床阶段的原创新药研发企业，致力于在肿瘤、乙肝及与衰老相关的疾病等治疗领域开发创新药物。公司拥有自主研发的蛋白-蛋白相互作用靶向药物设计平台。亚盛医药研发产品管线主要专注细胞凋亡路径关键蛋白的抑制剂，通过抑制BCL-2、IAP或MDM2-p53等，重启肿瘤细胞的凋亡程序；第二代和第三代的针对癌症治疗中出现的激酶突变体的抑制剂等。公司现有8个新药项目已进入到中国、美国及澳大利亚的I-II期临床开发阶段。 更多相关信息请浏览公司官网www.ascentagepharma.com

Rockville, Maryland and Hong Kong—January 8, 2019—Ascentage Pharma, a global clinical-stage biopharmaceutical company dedicated to developing apoptosis-targeted therapies for cancers and other diseases, today announced that Unity Biotechnology, Inc. (Nasdaq:UBX) has selected one of Ascentage’s compounds as its lead development candidate in its ophthalmology pipeline to advance into further preclinical studies to enable an Investigational Read More ›

Rockville, MD and Hong Kong, and Houston—January 6, 2019—Ascentage Pharma Group, Inc., and The University of Texas MD Anderson Cancer Center today announced a five-year strategic collaboration agreement to advance the development of five potential new cancer therapies. The alliance is aimed at developing novel cancer therapeutics based upon Ascentage’s proprietary Protein-Protein Interaction drug discovery Read More ›

ROCKVILLE, Md. and SUZHOU, China, — December 19, 2018 — Ascentage Pharma, a global clinical-stage biopharmaceutical company dedicated to developing apoptosis-targeted therapies for cancers and other diseases, today announced that it has entered into a strategic collaboration with Genor Biopharma Co. Ltd. (“Genor”). As part of the agreement, the companies will explore the synergies of Ascentage’s MDM2-p53 inhibitor, APG-115, and Genor’s Read More ›

SAN DIEGO, CA–December 3, 2018–Ascentage Pharma, a clinical-stage biopharmaceutical company dedicated to the development of novel therapies for the treatment of cancers, hepatitis B and aging-related diseases, today announced data from a Phase 1 clinical study of its novel BCR-ABL inhibitor, HQP1351, in patients with Tyrosine Kinase Inhibitor (TKI)-refractory chronic myelogenous leukemia (CML) at the Read More ›

SUZHOU, China and HONG KONG and ROCKVILLE, Md., Nov. 21, 2018 /PRNewswire/ — Ascentage Pharma, a clinical-stage biopharmaceutical company dedicated to the development of small molecule therapies for the treatment of cancers, hepatitis B and aging-related diseases, announced today that the Company will present clinical data of its novel BCR-ABL inhibitor HQP1351 in the upcoming 60th Annual Meeting of the American Society of Read More ›

ROCKVILLE, Md. and HONG KONG, CHINA /PRNewswire/ – Ascentage Pharma, a global clinical-stage biopharmaceutical company dedicated to developing apoptosis-targeted therapies for cancers and other diseases, today announced that interim results from two clinical programs will be presented at the 2018 American Society of Clinical Oncology (ASCO) annual meeting in Chicago, June 1-5, 2018. The poster sessions Read More ›

ROCKVILLE, MD and HONG KONG, CHINA /PRNewswire/ – Ascentage Pharma, a global clinical-stage biopharmaceutical company dedicated to developing apoptosis-targeted therapies for cancers and other diseases, today announced that research on its pipeline of small molecule therapeutics will be presented at the 2018 American Association for Cancer Research (AACR) annual meeting in Chicago, April 14-18, 2018. “The Read More ›

ROCKVILLE, Md. and HONG KONG, CHINA /PRNewswire – Ascentage Pharma, a global clinical-stage biopharmaceutical company dedicated to developing apoptosis-targeted therapies for cancers and other diseases, today announced the presentation of preliminary data from its ongoing Phase 1 trials of its lead product candidate APG-1252, a novel Bcl-2/Bcl-xL dual inhibitor. The data will be presented by Dajun Yang, Read More ›