Circulars & Announcements
2021
Presentation by Ascentage Pharma of Results of Latest Preclinical Studies at 2021 American Association for Cancer Research (AACR) Annual Meeting which Demonstrate Potential of Multiple Combination Therapies
April 13, 2021
Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 March 2021
April 9, 2021
CLARIFICATION ANNOUNCEMENT IN RELATION TO RESIGNATION OF NON-EXECUTIVE DIRECTOR AND
APPOINTMENT OF INDEPENDENT NON-EXECUTIVE DIRECTOR
April 1, 2021
ANNOUNCEMENT OF ANNUAL RESULTS FOR THE YEAR ENDED DECEMBER 31, 2020
March 31, 2021
List of directors and their roles and functions
March 31, 2021
RESIGNATION OF NON-EXECUTIVE DIRECTOR AND APPOINTMENT OF INDEPENDENT NON-EXECUTIVE DIRECTOR RESIGNATION OF NON-EXECUTIVE DIRECTOR
March 31, 2021
Ascentage Pharma’s First Third-Generation BCR-ABL Inhibitor in China Olverembatinib (HQP1351) Recommended for Breakthrough Therapy Designation
March 24, 2021
NOTICE OF BOARD MEETING
March 19, 2021
CLARIFICATION ANNOUNCEMENT IN RELATION TO GRANT OF AWARDS UNDER THE RSU SCHEME
March 19, 2021
Monthly Return of Equity Issuer on Movements in Securities for the month ended 28 February 2021
March 5, 2021
Next Day Disclosure Return
February 11, 2021
CLOSING OF PLACING OF EXISTING SHARES AND TOP-UP SUBSCRIPTION OF NEW SHARES UNDER GENERAL MANDATE
February 11, 2021
PLACING OF EXISTING SHARES AND TOP-UP SUBSCRIPTION OF NEW SHARES UNDER GENERAL MANDATE
February 4, 2021
Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 January 2021
February 3, 2021
Adoption of the 2021 RSU scheme
February 2, 2021
Voluntary Announcement -APG-2575 Granted the Fifth Orphan Drug Designation by the US FDA
January 29, 2021
Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 December 2020
January 6, 2021
Voluntary Announcement -Ascentage Pharma Obtained its 9th Orphan Drug Designation from the US FDA in 2020, Setting a Record among Chinese Biopharmaceutical Companies
January 5, 2021
2020
Voluntary Announcement -Received Milestone Payment for the Partnership with UNITY Biotechnology
December 22, 2020
Voluntary Announcement -Announcement of Updates on the Clinical Development of APG-2575, Including An Objective Response Rate of 70% in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia
December 10, 2020
Voluntary Announcement -Positive Data from Pivotal Phase II Studies of HQP1351 (Olverembatinib) was Announced at 2020 American Society of Hematology Annual Meeting
December 8, 2020
Monthly Return of Equity Issuer on Movements in Securities for the month ended 30 November 2020
December 3, 2020, 2020
Voluntary Announcement -Phase IIa Clinical Study of APG-115 as Single Agent or in Combination with APG-2575 Receives Clearances in China and the U.S.
December 2, 2020
Clarification Announcement
December 1, 2020
Voluntary Announcement -Entry into of an Agreement with the University of Michigan to Obtain An Exclusive License for a MDM2 Protein Degrader Using PROTACs Technology
November 30, 2020
Next Day Disclosure Return
November 25, 2020
Voluntary Announcement -APG-2575 Completed Dosing of the First Patient in Europe in Phase Ib/II Clinical Study
November 25, 2020
Voluntary Announcement -APG-2575 Receives Approvals for Two Phase Ib/II Clinical Studies in China
November 23, 2020
Voluntary Announcement -Ascentage Pharma Accepted for the Third Time to Release Updated Clinical Data of HQP1351 (Olverembatinib) in Drug-Resistant Chronic Myeloid Leukemia in an Oral Presentation at the American Society of Hematology Annual Meeting
November 9, 2020
Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 October 2020
November 4, 2020
Voluntary Announcement -APG-115 Granted Approval for the Phase Ib/II Clinical Study in China
October 27, 2020
Voluntary Announcement -Olverembatinib (HQP1351) of Ascentage Pharma is Included in the List of “Priority Review
October 21, 2020
Voluntary Announcement -APG-115 and APG-1252 Granted Orphan Drug Designation by the US FDA
October 9, 2020
Monthly Return of Equity Issuer on Movements in Securities for the month ended 30 September 2020
October 7, 2020
Grant of Awards under the RSU Scheme
September 16, 2020
Voluntary Announcement -APG-115 Granted Orphan Drug Designation by the FDA for the Treatment of Gastric Cancer
September 14, 2020
2020 Interim Report
September 14, 2020
Voluntary Announcement -APG-2575 Granted Second Orphan Drug Designation by the US FDA
September 7, 2020
Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 August 2020
September 3, 2020
Announcement of Unaudited Interim Results for the Six Months Ended June 30,2020
August 18, 2020
Voluntary Announcement -Becoming A Constituent of the Hang Seng Family of Indexes
August 17, 2020
Notice of Board Meeting
August 6, 2020
Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 July 2020
August 5, 2020
Voluntary Announcement – APG-115 Completed Dosing of the First Patient in Phase Ib Clinical Study in China
July 22, 2020
Voluntary Announcement – APG-2575 Granted Orphan Drug Designation by the US FDA
July 15, 2020
Next Day Disclosure Return
July 15, 2020
Closing of Placing of New Shares under General Mandate
July 15, 2020
2019 Environmental, Social and Governance Report
July 13, 2020
Placing of New Shares under General Mandate
July 8, 2020
Monthly Return of Equity Issuer on Movements in Securities for the month ended 30 June 2020
July 6, 2020
Voluntary Announcement – Clinical Collaboration with MSD
July 6, 2020
Voluntary Announcement – Clinical Collaboration with Acerta Pharma, the Hematology Research and Development Center of Excellence of AstraZeneca
June 22, 2020
Poll Results of the Annual General Meeting Held on June 19, 2020
June 19, 2020
Voluntary Announcement – Submission of New Drug Application for HQP1351 in China
June 18, 2020
Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 May 2020
June 3, 2020
Voluntary Announcement – Latest Clinical Data of Apoptosis Targeting Drug Candidates was Presented at 2020 American Society of Clinical Oncology (ASCO) Annual Meeting
May 31, 2020
Voluntary Announcement – HQP1351 Granted Fast Track Designation by the US FDA
May 7, 2020
Monthly Return of Equity Issuer on Movements in Securities for the month ended 30 April 2020
May 6, 2020
Voluntary Announcement – HQP1351 Granted Orphan Drug Designation by the U.S. FDA
May 4, 2020
Form of Proxy for the Annual General Meeting to Be Held on June 19, 2020
April 17, 2020
Notice of Annual General Meeting
April 17, 2020
2019 Annual Report
April 17, 2020
Proposed Re-election of Retiring Directors and Proposed Granting of General Mandates to Issue Shares and Repurchase Shares and Notice of Annual General Meeting
April 17, 2020
Voluntary Announcement – Approval for the Phase Ib/II Clinical Study of APG-2575 in China
April 7, 2020
Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 March 2020
April 6, 2020
Announcement of Annual Results for the Year Ended December 31, 2019
March 29, 2020
Voluntary Announcement – APG-2575 completed dosing of first patient in Phase Ib/II trial in the U.S.
March 23, 2020
Notice of Board Meeting
March 12, 2020
Voluntary Announcement – Approvals obtained in China and U.S. for three phase Ib/II clinical trials of APG-2575
March 9, 2020
Monthly Return of Equity Issuer on Movements in Securities for the month ended 29 February 2020
March 4, 2020
Voluntary Announcement – Approval of phase Ib/II clinical trial of APG-1387 for the treatment of advanced pancreatic cancer in combination with chemotherapy in China
February 24, 2020
Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 January 2020
February 6, 2020
Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 December 2019
January 3, 2020
Voluntary Announcenment – Studies of HQP1351 nominated the “Best of ASH” at the 2019 American Society of Hematology Annual MeetingDecember 11, 2019 |
Monthly Return of Equity Issuer on Movements in Securities for the month ended 30 November 2019December 4, 2019 |
Next Day Disclosure ReturnNovember 25, 2019 |
FULL EXERCISE OF THE OVER-ALLOTMENT OPTION,STABILISING ACTIONS AND END OF STABILISATION PERIODNovember 21, 2019 |
Monthly Return of Equity Issuer on Movements in Securities for the month ended 31 October 2019November 06, 2019 |
Amended and Restated Memorandum and Articles of AssociationOctober 25, 2019 |
Terms of Reference for Nomination CommitteeOctober 25, 2019 |
Terms of Reference for Audit CommitteeOctober 25, 2019 |
Terms of Reference for Remuneration CommitteeOctober 25, 2019 |
List of Directors and their Roles and FunctionsOctober 25, 2019 |
Procedures for election as directorOctober 25, 2019 |
Board Diversity policyOctober 25, 2019 |
Shareholders Communication PolicyOctober 25, 2019 |
Global Offering – Allotment ResultsOctober 25, 2019 |